Synonymous Substitutions Substantially Improve Evolutionary Inference from Highly Diverged Proteins
نویسندگان
چکیده
منابع مشابه
Synonymous substitutions substantially improve evolutionary inference from highly diverged proteins.
Codon-and amino acid-substitution models are widely used for the evolutionary analysis of protein-coding DNA sequences. Using codon models, the amounts of both nonsynonymous and synonymous DNA substitutions can be estimated. The ratio of these amounts represents the strength of selective pressure. Using amino acid models, the amount of nonsynonymous substitutions is estimated, but that of synon...
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ژورنال
عنوان ژورنال: Systematic Biology
سال: 2008
ISSN: 1076-836X,1063-5157
DOI: 10.1080/10635150802158670